CLINICAL EVIDENCE

Explore peer-reviewed research, clinical trials, and real-world data supporting the efficacy and safety of the BEAR Implant

THE BEAR IMPLANT IS SUPPORTED BY LEVEL 1 CLINICAL EVIDENCE.

At 2 years, all primary and secondary study endpoints were met.

PRIMARY OUTCOMES

IKDC

The BEAR Implant is similar to reconstruction at 2 years.

IKDC outcome comparison data chart

AP LAXITY

Side-to-side difference for BEAR Implant is the same as ACLR at 2 years.

AP Laxity outcome comparison data chart

SECONDARY OUTCOMES

HAMSTRING STRENGTH

The BEAR Implant provides statistically better hamstring strength at 6 and 12 months, with the trend sustained to 2 years (shown).

Hamstring strength outcome data

CONTRALATERAL TEARS

BEAR Implant patients experience a trend toward fewer contralateral ACL tears at 2 years.

Contralateral ACL tears outcome data
Skier

RESULTS ARE VALIDATED BY MRI AND PRECLINICAL HISTOLOGY.

LONGITUDINAL MRIs

Longitudinal MRI results

BEAR Implant restores the torn ACL

ACL ORIENTATION COMPARISON

ACL Orientation Comparison

ACL restored to similar orientation of native ACL

HISTOLOGY

Histology Image

By 8 weeks the BEAR Implant is replaced with native cells, new collagen and blood vessels

Case Studies

Dr. Jonathan Glashow Second Look Case Study

This case study uses second-look arthroscopic imaging to demonstrate successful restoration of the native ACL, revealing healthy and robust tissue at just 3 months post-op.

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Dr. Brian Lau Partial Tear MRI Case Study

Explore this partial ACL tear case in which post-operative MRI imaging revealed a healed native ACL, supporting a successful return to activity at 9 months.

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Dr. Jeffrey Abilgaard Second Look Case Study

Review this case study in which a second look lysis of adhesions surgery, in addition to 5-month post-op MRIs, revealed a strong, intact ligament.

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Dr. Sean Keyes Physeal Sparing Case Study

Discover how a physeal-sparing BEAR Implant technique helped a 12-year-old competitive swimmer restore his native ACL, with post-operative MRI and X-rays confirming healing without physeal arrest or leg length variation.

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Publications

Over 30 papers, including literature reviews, case studies, analyses of pivotal data, and surgical technique videos have been published on BEAR Implant. This selection of key literature highlights the safety, efficacy, and benefits of the BEAR Implant.

We are committed to expanding our growing base of evidence on BEAR through our ongoing clinical studies

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