Medical Professionals

BEAR® Implant

The Bridge-Enhanced® ACL Repair (BEAR®) Implant is a proprietary bio-engineered bridging scaffold to facilitate healing of the torn ACL.

The BEAR Implant is designed to be surgically placed between the torn ACL ends at the time of repair, and to hold a small amount of the patient’s blood in the wound site. The combination of the BEAR Implant and the patient’s blood provides a scaffold that allows the torn ends of the ACL to heal back together.

Illustration of the BEAR® implant process. Figure 1: Torn ACL. Figure 2: Place BEAR® implant between torn ACL ends. Add blood. Figure 3: Pull torn ACL ends into implant with stitches. Figure 4: Healing ACL tissue replaces BEAR® implant.

It is hoped this new technology will restore more normal anatomy and function of the knee, and thus enable a higher percentage of patients to get back to activities they enjoy.

The BEAR Implant is an investigational device and is only available in FDA-approved clinical trials.

Watch this video to find out more about how the BEAR Implant works.

Watch this video to find out more about ACL tears, the BEAR Implant and the first patient to receive it.

Listen to this podcast to hear about the development of the BEAR Implant and clinical trial results.

BEAR Clinical Trials

Several clinical trials are underway to study the BEAR implant and its safety and efficacy.

Publications

Clinical Study Results

Higher Physiologic Platelet Counts in Whole Blood Are Not Associated With Improved ACL Cross-sectional Area or Signal Intensity 6 Months After Bridge-Enhanced ACL Repair
Orthopaedic Journal of Sports Medicine, July 2020

Females Have Earlier Muscle Strength and Functional Recovery After Bridge-Enhanced Anterior Cruciate Ligament Repair
Tissue Engineering Part A, June 25, 2020 (Ahead of Print)

Bridge-Enhanced Anterior Cruciate Ligament Repair Is Not Inferior to Autograft Anterior Cruciate Ligament Reconstruction at 2 Years: Results of a Prospective Randomized Clinical Trial
American Journal of Sports Medicine, May 2020

Changes in Cross-sectional Area and Signal Intensity of Healing Anterior Cruciate Ligaments and Grafts in the First 2 Years After Surgery
American Journal of Sports Medicine, June 2019

Predictors of Healing Ligament Size and Magnetic Resonance Signal Intensity at 6 Months After Bridge-Enhanced Anterior Cruciate Ligament Repair
American Journal of Sports Medicine, April 2019

Bridge-Enhanced Anterior Cruciate Ligament Repair: Two-Year Results of a First-in-Human Study
Orthopedic Journal of Sports Medicine, March 2019

Bench-to-Bedside: Bridge-Enhanced Anterior Cruciate Ligament Repair
Journal of Orthopaedic Research, July 2017

The Bridge-Enhanced Anterior Cruciate Ligament Repair (BEAR) Procedure: An Early Feasibility Cohort Study
Orthopedic Journal of Sports Medicine, November 2016

Preclinical Study Results

Use of a Bioactive Scaffold to Stimulate Anterior Cruciate Ligament Healing Also Minimizes Posttraumatic Osteoarthritis After Surgery
American Journal of Sports Medicine, August 2013